SYLLABUS OF PATHOPHYSIOLOGY (2nd SEM BPHARM) :-

                                       SUBJECT:-

                             PATHOPHYSIOLOGY

                              (SUB CODE-BP204T,BPHARM 2nd SEM,PCI)

Unit I :-

 Basic principles of Cell injury and Adaptation: Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – 

Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,Electrolyte imbalance.

 Basic mechanism involved in the process of inflammation and repair: Introduction, Clinical signs of inflammation, Different types of Inflammation,Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s,Mediators of inflammation,Basic principles of wound healing in the skin,Pathophysiology of Atherosclerosis

Unit II :-

 Cardiovascular System: Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial infarction, atherosclerosis and arteriosclerosis) 

 Respiratory system:Asthma, Chronic obstructive airways diseases.

 Renal system:Acute and chronic renal failure .

Unit III :- 

 Haematological Diseases: Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia 

 Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones 

 Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease. 

 Gastrointestinal system: Peptic Ulcer 

 Unit IV :-

 Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease. 

 Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout  Principles of cancer: classification, etiology and pathogenesis of cancer 

 Diseases of bones and joints:Rheumatoid Arthritis, Osteoporosis,Gout

 Principles of Cancer: Classification, etiology and pathogenesis of Cancer

Unit V :- 

 Infectious diseases:Meningitis,Typhoid, Leprosy, Tuberculosis ,Urinary tract infections

 Sexually transmitted diseases:AIDS, Syphilis, Gonorrhea

                                                              END